HOLLYWOOD—Famous actor, stand-up comedian and star of “The Larry Sanders Show,” Garry Shandling, died on Thursday, March 24 from a massive heart attack, according to a report from TMZ. There was a 911 call from Shandling’s home and he was transported to a Los Angeles hospital where he died.

Shandling passed away at the age of 66 after a long Hollywood career. He was known not only for starring and writing for “The Larry Sanders Show,” but also for “What Planet Are You From?” and “It’s Garry Shandling’s Show.” “The Larry Sanders Show” was a satiric look behind the scenes of a late night comedy talk show that ran from 1992-1998.

Many famous comedians shared their feelings on the loss of Shandling on social media. “He inspired an entire generation of comedians,” tweeted late night show host Conan O’Brien.

Judd Apatow, director of “Trainwreck” and “The 40-Year-Old Virgin,” posted a picture of himself and Shandling on Instagram with the caption, “Goodbye Garry. We love you.”

Shandling was born on November 29, 1949 in Chicago, Illinois. He wrote for “Sanford and Sons” and “Welcome Back, Kotter” in the 70s during his career. At one point he turned down an offer from NBC to take over the Late Night Show after David Letterman left, according to his bio on the International Movie Database.