Cain struck out a career-best 14 batters, tying the legendary Sandy Koufax for most Ks in a perfect game.
History was preserved in the 7th inning after right fielder Gregor Blanco made a highlight reel catch on a deep drive to right-center field.
Cain's perfect game is the first in the 128-year history of the franchise, and the Giants' first no-hitter since Jonathan Sanchez in 2009.
This is the second perfect game of the season. Phil Humber of the Chicago White Sox pitched a perfect game on April 21. This is also the fifth no-hitter of the season in the majors.
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