LOS ANGELES—Actor Powers Boothe, known for notable roles in “Guyana Tragedy,” “Sin City,” and “Agents of S.H.I.E.L.D.,” died in his sleep from natural causes on Sunday, May 14, at his Los Angeles home. He was 68.

Longtime friend, actor Beau Bridges, shared the news through Twitter, stating, “It’s with great sadness that I mourn the passing of my friend Powers Boothe. A dear friend, great actor, devoted father & husband.”

Powers Allen Boothe was born on June 1, 1948, in Snyder, Texas. After graduating from Southwest Texas State University, he began his acting career with the Oregon Shakespeare Festival, with a portrayal of Henry IV. He made his Broadway debut in 1979 in James McLure’s “Lone Star.”

In 1980, Boothe gained national recognition for his performance as cult leader Jim Jones in the CBS film, “Guyana Tragedy: The Story of Jim Jones,” for which he won the Emmy Award for Outstanding Lead Actor. He accepted his award during the Screen Actor Guild’s Strike, when other actors boycotted the awards ceremony.

In 1983, Boothe played the title character in Raymond Chandler’s “Philip Marlowe, Private Eye.” He appeared in films including “Red Dawn” (1984) and “Into the Homeland” (1987), which earned him a nomination for a CableACE Award. He became known for his portrayals of villains, such as Curly Hill Brocius in “Tombstone,” Joshua Foss in “Sudden Death,” and Cy Tolliver in the HBO series “Deadwood.” In 2005, he took on the role of the corrupt politician, Senator Roark, in “Sin City” and reprised the role in the 2014 sequel.

More recently, Boothe appeared in the 2012 film “The Avengers” and the ABC series “Agents of S.H.I.E.L.D.” as Gideon Malick, a member of the World Security Council and secret leader of Hydra. He also portrayed Lamar Wyatt in the drama “Nashville,” as a widow and former mayor of Nashville.

Friends and fans took to social media to share their condolences for the late actor.

Boothe is survived by his wife, Pam, and two children, Parisse and Preston. A private service will be held in his honor in Texas, and a memorial service is under consideration. Donations can be made to the Gary Sinise Foundation, in honor of the nation’s veterans, defenders, first responders, and their families, according to a statement released by representative Karen Samfilippo.